Ok so I skimmed over my fertilization/embryo one-page report after Transfer, but never looked very close.
Also, I just re-read my HCG trigger dose.
I have concerns about both in terms of the doctor's communication. The HCG I think was done wrong (I got a 2500 dose rather than 5000). The embryo thing, I think they just didn't communicate as well as I'd have liked.
Can you guys give me thoughts?
HCG trigger: My Estradiol level at Day 10 of meds came back at 4944. I had a follicle over 21mm & ones close behind, which was the cutoff for trigger. The dr said b/c I had such a high E2 level, he didn't want me on the whole HCG dose just so the smaller follicles wouldn't catch up & me possibly overstim. Fair. However, the regular 10,000 does instruction paper says:
Mix 1 ML water w/ powder. Draw 1 ML mix into needle. Inject 1ML.
My dr scratched out & wrote:
Mix 2 ML water w/ powder. Draw 1 ML mix into needle. Inject 1ML.
Now do the math. I doubled the water & then injected half. By doing both I got 2500 HCG (when he clearly wrote & told me 5000). Right? Shouldn't he have said mix 1 ML water & inject 1/2 ML? Or have you guys done this & it's right?
Embryo Fertilization: We were told we had 17 eggs retrieved, 15 mature, 8 fertilized (1 latecomer). Maybe the dr DID mutter something about others than fertilized & wouldn't have been normal, it was hard to hear. My sheet says:
7 fertilized w/ 2 pronuclei
1 fertilized w/ 1 pronuclei (don't know which one that was)
3 fertilized w/ 3 pronuclei (multinucleation, I think this is called)
So honestly we got a better fert rate than I thought (11 out of 15), but just some abnormal embryos, i.e. non viable. Isn't that interesting? Has anyone else gotten this? I don't know if this is good or bad, 3 sounds like a lot to have an extra pronuclei, therefore a whole extra set of chromosomes. Bad eggs? Not a clue! Who knows something?
And no I'm not upset or even worried. Just interesting! If there's a next time, I'm totally reading this stuff ahead of time (not like they gave me a chance too, I got the paper as I left ET!)
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Sorry, I'm no good at math, and I didn't have to mix my own HCG, so I can't help you with the question about the dose.
I might have missed this somewhere, but do you know yet if you ended up with any frozen embryos?
Well, my thought about the hCg is that it still worked out okay because you got 15 mature eggs. 4944 is a high estradiol level so he was right to try to avoid overstim....that would've sucked because not only do you feel like crap but it can delay your transfer.
I'm not using pregnancy tests at all this cycle because I just can't deal with the disappointment if it is negative. (Talk about denial!)
And are you giving yourself the PIO shots?? If so you are more of a woman than me! JW has to give them to me each night.
Can't wait to hear your beta results! I'm keeping all my fingers and toes crossed for you!
Your HCG was correct. If you take 10,000 units and dilute it in 2 ml of water, then you have 5,000 units per ml. You injected 1 ml so you got 5,000 units. If you had diluted with 1 ml and injected 1/2 ml you also would have gotten 5,000 units. But the bigger dilution allows for slightly better accuracy in the drawing up the meds. Hope that helps.
I have less confidence in this part: with the fert report, I think they only consider "normal" embryos in the fert rate. But I think sometimes single pronuclei ones can go on to divide normally? Something like that. So that would give you 8. I'm not sure what can be considered typical for 2 pronuclei.
Good luck!
So this might be too much information to share on a blog but how in the world do you give yourself a PIO shot?? Do you do it in your thigh? We are doing mine in the hip/butt area. I can't even see where he is injecting so I'm not sure how I would do it myself. I would actually rather give myself the shots because I'm a control freak like that.
So this might be too much information to share on a blog but how in the world do you give yourself a PIO shot?? Do you do it in your thigh? We are doing mine in the hip/butt area. I can't even see where he is injecting so I'm not sure how I would do it myself. I would actually rather give myself the shots because I'm a control freak like that.
Yep, Waiting Amy has it right. I have always done mine that way by mixing with 2 and then only injecting 1. My doc uses that leftover 1 for a booster shot if its needed later.
You sound like things are going great! Think positive. We are all here for you.
:)
Yeah, all that I read was, 'blah blah blah blah blah'... it's like a foreign language to me! But I wanted to comment anyway just so that you know that I'm thinking really big, fat positive thoughts for you. I wanted to e-mail you with a question, but someone doesn't have an e-mail me button... so you e-mail me, and I'll respond... hahaha.
Good luck! I'm gearing up for IVF #1 soon - same diagnois - unexplained IF.
I haven't been through IVF, so I am no good to you as far as your questions go. But what I am good for is sending prayers your way, which I am doing right now!
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